Her expertise includes epidemiology, genomics, and statistics, which she applies to complex disorders such as cancer and cardiovascular diseases. She specializes in mining large genomics and epidemiological datasets from diverse populations to discover genetic and environmental factors that predispose to disease and may differ between different ancestries. Tcheandjieu is a recipient of the Stanford Postdoc Justice, Equity, Diversity, and Inclusion (JEDI) Champion Award, the Stanford Jump Start Award, and the Million Veteran Program early career investigator award. She was also the winner of the 2022 Bench to Bassinet Pediatric Cardiac Genomics Consortium (PCGC) and Cardiovascular Development Data Resource Center (CDDRC) Challenge Prize. She is a co-founder of BlackInCardio.