Dr. Andrews is a genetic epidemiologist looking at the role of genetic and environmental risk factors in Alzheimer's disease. The Andrews Lab focuses on determining the causal pathways that underly the development of Alzheimer’s disease and related dementias (ADRD) by applying statistical genetic and genetic epidemiological approaches to large genetic & phenotypic datasets. Currently funded NIH-NIA and Alzheimer’s Association projects include (1) identifying causal risk factors for ADRD using genetic correlations, polygenic risk scores, and mendelian randomization; (2) understanding the role of mitochondrial genomics in ADRD pathogenesis; and (3) evaluating ancestry specific effects of AD genetic variants on AD endophenotypes.